شف آنلاین>سلامت>محققان از کشف پروتئینی خبر دادند که حذف ژنتیکی آن می تواند نقش اساسی در درمان آلزایمر داشته باشد.
به گزارش
شفا آنلاین،
از پایگاه اینترنتی یاهو نیوز،
این پروتئین که به GPR3 معروف است، سبب تجمع پلاک های آمیلوئید در مغز می
شود که از مشخصه
بیماری آلزایمر است.
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)
محققان با تحقیق روی موش های دارای
چهار نوع مختلف از زوال عقل، متوجه شدند که حذف ژنتیکی این پروتئین سبب
بهبود عملکرد شناختی و کاهش علایم بیماری در مغز می شود.
همچنین
کالبدشکافی مغز اجساد انسان های مبتلا به آلزایمر نشان می دهد که افزایش
سطح این پروتئین، با سرعت روند پیشرفت آلزایمر در ارتباط است.
اما از
آنجایی که الگوی بیماری آلزایمر در موش ها دقیقا مشابه انسان ها نیست، برای
تایید این موضوع در مورد انسان ها به تحقیقات بیشتری نیاز است.
در حال
حاضر هیچ درمانی برای بیماری آلزایمر که شایع ترین نوع زوال عقل است، وجود
ندارد و هیچ دارویی نتوانسته است مانع پیشروی این بیماری شود.
بیش از 46
میلیون نفر در سراسر جهان به زوال عقل مبتلا هستند و انتظار می رود که
موارد ابتلا به این بیماری تا سال 2050 به دلیل پیر شدن جمعیت جهان به
131.5 میلیون نفر برسد.
نتایج این تحقیق در نشریه Science Translational Medicine منتشر شده است.ایرنا